In this paper, the global controllability for a class of high dimensional polynomial systems has been investigated and a constructive algebraic criterion algorithm for their global controllability has been obtained. By the criterion algorithm, the global controllability can be determined in finite steps of arithmetic operations. The algorithm is imposed on the coefficients of the polynomials only and the analysis technique is based on Sturm Theorem in real algebraic geometry and its modern progress. Finally, the authors will give some examples to show the application of our results.